Skin Booster

K Booster

NO.1 SKIN BOOSTER IN KOREA.

A NEW STANDARD SKIN BOOSTER FOR SKIN REJUVENATION.

IDEAL ECM SKINBOOSTER FOR DERMAL BIOGENESIS.

OPTIMAL BIOSTIMULATING FORMULAR FOR DERMAL FIBROBLAST.

When a flower doesn't bloom, you fix the environment in which it grows, not the flower

Alexander Den Heijer

K-Booster Can Improving of Dermal ECM Environment (Ha+54 Essential Ingredient)

Healthy Skin

Aging Skin

Effects of Photodamage and Aging

k-Booster is Optimal Biostimulating formular for Dermal Fibroblast (Growth Factor)

FIBROBLAST ROLE

Fibroblast is a Key Maintainer of ECM Networks

Polycomponent Mesosolution + HA + Growth Factor = K Booster

FIBROBLAST

Fibroblast Stimulation → Collagen, Elatin Formation

K Booster indication

  • +for men and women of all skin type
  • +for people with younger or more mature skin
  • +for the face, neck, hands & decolletage
  • +for people improve acne scarred or photodamaged skin

01 K-Booster A AQUA

INCLUDE 4 kinds of Growth factors

+Hyaluronic acid (0.3%)

+12 Vitamines

24 Amino acids

6 Co-enzymes

6 Minerals

5 Nucleic acid

1 Anti-oxidant

+EGF | IGF-1 | bFGF | AQP

INDICATION

  • Skin Hydration
  • Improve Radiance
  • Skin Revitalization
  • Biostimulation of Dermal Fibroblast

02 K-Booster R REJUVENATION

INCLUDE 20 kinds of Growth factors

+Hyaluronic acid (0.5%)

+12 Vitamines

24 Amino acids

6 Co-enzymes

6 Minerals

5 Nucleic acid

1 Anti-oxidant

+EGF | IGF-1 | bFGF | AQP | aFGF | VEGFA | PDGFA | PDGFB | PGF | SCF | COL3A1 | KGF | hGH | HSP70 | SIRT1 | SIRT2 | SOD | TRX | TGF-b1 | TGF-b3

INDICATION

  • More Powerful Hydration
  • Rediance & Revitalization
  • Biostimulation of Fibroblast
  • Remove Fine Line
  • Scar Treatment

03 K-Booster W WHITENING

INCLUDE 2 kinds of Plant callus extracts

+Hyaluronic acid (0.5%)

+12 Vitamines

24 Amino acids

6 Co-enzymes

6 Minerals

5 Nucleic acid

1 Anti-oxidant

+Citrus Junos Callus Extract

Pyrus Serotina Callus Extract

INDICATION

  • Hydration
  • Radiance
  • Improve Skin Tone
  • Reduce Melasma

Provides optimal environment for skin cells

A new concept solution that creates an environment that helps grow cells. It provides an abundant nutrient and proper pH concentration, osmotic pressure, etc. for skin cells to grow well, creating an environment where healthy skin cells can grow and grow.

01 Amino acid Complex

Amino acid is an essential component of skin and human body and is the most powerful NMF(natural moisturizing factor) that exists in nature.

02 Mineral Complex

Minerals are inorganic nutrients. It is an important substance that constitutes our body. It is an oxygen carrier that carries the oxygen that is in the body to the necessary place. Helps keep skin cells healthy and helps prevent aging. Moisturizes dry skin and helps to calm troubles & sensitive skin.

03 Vitamin Complex

The antioxidant effect of vitamins A, B, C, and E Complex removes harmful free radicals and reduces skin stress.

04 High purify hyaluronic acid

Hyaluronic acid is the most important ECM component. It improves the ECM environment and improves the moisturizing and elasticity of the skin.

05 Growth Factor Complex

As the aging process progresses, the essential ingredients are blended in an optimum ratio to maintain a healthy skin condition.

06 Safety & No pain

The same osmotic and pH conditions as skin. No swelling, fever, pain or irritation. GMP manufacturing production, Formulation optimized for cell culture No cytotoxicity and no sterilization process

Development Background

We want to develop an optimal solution to improve the ECM environment of the dermis and to promote the growth of human keratinocytes to suppress aging.

01 K-complex optimal combination The optimal booster combination was found through cell testing of various combinations of booster.

Fig 1. The effect of K-Complex on human keratinocytes

The cytotoxicity and cell proliferation of human keratinocytes were tested by MIT assay. As a result, it was confirmed that the combination of No. 8 test group showed about 180% cell proliferation ability compared with the control group.

02 Comparative test As a result of comparing with the product of A company, K-complex was not cytotoxic even in 50% treatment group.

A

B

Fig 2. Comparison of K-Complex with product A

A comparative test of the basic base composition of product A (A) and K-Complex (B) was tested in human keratinocytes. As a result, it was confirmed that K-Complex does not show cytotoxicity even at a higher concentration than the product A.

03 Optimization of K-Booster 1 For maximize cell proliferation, K-complex combined with optimal combination of growth factors. It was branded as K-Booster.

Fig 3. Effect of K-Booster on human keratinocytes (1)

In order to enhance the efficacy of the K-Complex, the growth factor was tested in human keratinocytes by adding growth factors at an optimal ratio. As a result, it was confirmed that the cell proliferation effect was significantly enhanced when treated with the growth factor, rather than adding K-Complex alone.

04 Optimization of K-Booster II It improves product quality through sterilization process and is safer to skin.

Fig 4. Effect of K-Booster on human keratinocytes (2)

In order to commercialize K-Booster, 1,2-hexanediol was prescribed to confirm efficacy in the final product. As a result, it was confirmed that cell proliferation is promoted even in the final product.

Cell Test

05 Promotes skin cell proliferation and activity

The K-booster solution was treated up to 50% in human keratinocytes, Cell proliferation increased by about 40% compared to the control group.

A. Human keratinocyte proliferation test

Control

K-Booster treated

B. Human fibroblast proliferation test

Control

K-Booster treated

Fig 5. Effect of K-Booster on human skin cells

The proliferative potential of K-Booster in human skin cells was visually observed. As a result, the cell proliferation was significantly promoted in the K-Booster test group.

06 Promotes skin cell proliferation and activity

Promoting skin cell wound regeneration : K-Booster promotes wound regeneration in a concentration-dependent manner.

Control

K-Booster 6.25% treated

K-Booster 25% treated

Fig 6. Effect of K-Booster on wound regeneration in human keratinocytes

The wound regeneration effect of K-Booster in human keratinocytes was examined. As a result, it was confirmed that the woundregeneration rate was remarkably faster in the K-Booster 25% test group as compared with the control group.

Wrinkles in the eyes (at 2 weeks interval • 5 times)

Wrinkles in the eyes (at 2 weeks interval. 5 times)

Acne & trouble skin (at 2 weeks interval. 5 times)

Pigmentation (at 2 weeks interval. 5 times)

Flush & pore (at 2 weeks interval · 5 times)

Freckle (at 2 weeks interval • 5 times)

Freckle (at 2 weeks interval • 5 times)

Wrinkles in back of hand (at 2 weeks interval. 5 times)

further product information

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