PDO Filler

Rejubella

PDO dermal filler

01
PDO Microsphere

02
Safe & Quick Treatment

03
Natural Collagen Generation

04
Enhancement of Facial Health

A polymer filler made by a new form of PDO whose stability has been confirmed for over 40 years.

PDO dermal filler Rejubella aims to promote collagen production and maintain volume.
Rejubella improves the fundamental deficiency of volume by collagen restoration.

Specification

Patent 10-2019-0124485

Product of uniform size Microsphere PDO particles

PDO Microsphere Features

The surface is smooth spherical and even particle

Cannula size : 26G

Size : 10-60μm

Capacity : 300mg/vial,
1vial/box or 5vial/box

PDO(polydioxanone) 150mg

+

CMC 150mg

Surface area of one PDO microsphere : 0.00608mm2

Surface area of approximately 2.6 million PDO microspheres of Rejubella : 15,800mm2

=

Surface area of one PDO mono thread (USP6-0 50mm) : 11.0mm2

Similar effect to 1,436 PDO mono threads

1Week

4Weeks

Collagen Generation

PDO fillers stimulate the skin through normal metabolic processes in the body.

As the fibroblasts of the irritated skin are active, it promotes regeneration of collagen and various skin tissues, improving the volume and elasticity.

Function Comparison

# METABIOMED company A company B
Image
Main ingredient PDO (Polydioxanone) PCL (Polycaprolactone) PLLA (Poly-L-Lactic acid)
Component

PDO150mg

+

CMC150mg

PCL30%

+

CMC70%

PLLA150mg

+

CMC90mg

+

Mannitol127.5mg

Total capacity 300mg / 5ml* 1cc 367.5mg / 5ml*
Decomposition period 1 year 1~4 years 2~2.5 years
Particle size 10-60μm 25-50μm 40-63μm
Particle shape Uniform spherical Uniform spherical Sharp non-uniform
Type Powder Liquid Powder

Rejubella is a filler that consists of stable PDO microspheres developed by Metabiomed, and has fewer side effects and shorter preparation time compared to other companies.

Mechanism Process

1

Before Treatment

2

Making Volume

3

Back to Original State

4

Collagen Generation Increase of Dermal Thickness

How to use

1

Inject 5ml of sterile water into 1vial by a syringe with a sterile 18g needle.(add 1~2ml of lidocaine)

2

Shake enough to completely hydrate the product.

3

After shaking the vial to make a suspension, take an appropriate amount of the product with 1-3ml sterile syringe and a new 18g needle.

4

Use the product after connecting 26g needle to the syringe.

Safe & Biodegradable

0 day

1 week

1 month

2 month

3 month

5 month

6 month

METABIOMED

company A

company B

Ref) Osong Advanced Medical Innovation Foundation Laboratory Animal Center

Changes of filler volume

In the case of the product of companyA and companyB, it was confirmed that all substances in the body were biodegraded at the first month. And in the case of Rejubella, all substances in the body were biodegraded at the 5th month.

As Rejubella slowly biodegrades, the effect of self-generation lasts for a long time.

Self healing process stimulates collagen and elastin production during hydrolysis.

PDO powder filler Areas

Wrinkle improvement

  1. 1Frown Lines
  2. 2Brow(worry) Lines
  3. 3Eye Brow
  4. 4Crow’s Feet
  5. 5Nosolabial folds
  6. 6Marionette Lines

Volume

  1. 7Cheek Augmentation
  2. 8Fill temple depressions
  3. 9Chin Augmentation

Scaffold

  1. 10Nose

Whitening

Rejuvenation

further product information

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Rejubella

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