Orthopedics
BoneMedik-S
Coralline Hydroxyapatite Bone Graft Substitute
Advantages
- No Biological Rejection
- No Disease Transmission
- No Additional Surgery Necessary to Collect the Bone for Grafting
- Offer an Interconnected Porosity Similar to Human Cancellous Bone
- Provide a Framework Which the Host Bone can Regenerate & Heal
- USA- Patented Silicon Ion Containing HA Speeds Up the Bone Regeneration (Si-Content : Avg. 0.6wt%)
- Under Strict FDA Regulations & GMP Compliance, Ensuring the Highest Product Quality
AP(Alkaline Phosphate) Activity
This figure shows alkaline phosphate (AP) activity in human mesenchymal stem cells cultured on BD and BoneMedik-S.
AP is an enzyme whose activity refl ects diff erentiation of human mesenchymal stem cells to bone forming osteoblastic cells.
Higher AP activity means the human mesenchymal stem cells are diff erentiating towards the bone forming osteoblast phenotype to a greater degree.
Cells were cultured on calcium phosphate scaff old, Catalog No. 354617 (BD), BoneMedik-S scaff old (Coral).
The fact that AP is higher in human mesenchymal stem cells on BoneMedik-S (coral) than in human mesenchymal cells on BD suggest that cell on BoneMedik-S are better able to form bone than cells on BD.
These preclinical data suggest BoneMedik-S might be superior to other scaff olds in stimulating bone growth.
(Pre-Study in Penn State Hershey Milton. S. Medical Center in PA, USA / META R&D Institute, KOREA. 2009)
Eye Observation HA
1 Week
3 Week
6 Week
12 Week
24 Week
Micro Observation HA

De Novo Bone
Normal Bone
Eye Observation Si-HA
1 Week
3 Week
6 Week
12 Week
24 Week
Micro Observation Si-HA

Normal Bone
BoneMedik-S
Porosity %
pore Size μm
Compressive Strength Mpa
Clinical Test Results
Case 1Lumbar Interbody Cage


Case 2ACDF with Cervical Cage


Case 3Upper Tibial Osteotomy for Degenerative Arthritis Cage
Post-Operation


Degenerative Arthritis
Yoo.(F/49)
Knee joint degenerative arthritis High tibial osteotomy
8 months later


by courtesy of M.D.,Ph.D. Kim. Y.M (Prof.,C.B National University, 2008)
Specifications
Chip Type

Model No. | Volume | Size |
---|---|---|
BSC0320 | 3cc | 2~4mm |
BSC0520 | 5cc | |
BSC1020 | 10cc | |
BSC1520 | 15cc | |
BSC2020 | 20cc | |
BSC3020 | 30cc |
Chip / Cage Type

Model No. | Volume | Size |
---|---|---|
BSC0140 | 3cc | 4~6mm |
BSC0340 | 5cc | |
BSC0540 | 10cc | |
BSC1040 | 15cc | |
BSC1540 | 20cc | |
BSC2040 | 30cc | |
BSC3040 | - |
Block Type

BSB1001 10×10×10mm

BSB0502 5×12×40mm

BSB1003 10×10×40mm

BSB1004 10×20×50mm

BSB1205 12×25×25mm

BSB1206 12×30×30mm
Wedge Type

BSW0701 7(2)×15×30mm

BSW1002 10(2)×15×30mm

BSW1203 12(2)×15×30mm

BSW1504 15(2)×15×30mm
further product information
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